In snail organism tissues, glycosaminoglycans (GAGs) are mainly located inside granules and in the shell and are produced on the exterior of the shell as a mucous-like material. Snail glycosaminoglycan tightly unites divalent copper cations (Cu 2 ) that create copper peptides. This substance reportedly has skin regeneration abilities. The proportion of copper in the snail secretions is impressive.
Copper peptides have been shown to be effective in just small quantities:
Copper-induced vascular endothelial growth factor expression and wound healing. Sen CK, Khanna S, Venojarvi M, Trikha P, Ellison EC, Hunt TK, Roy S. 2002 May;282(5): H1821-7.
Laboratory of Molecular Medicine, Department of Surgery, 512 Davis Heart & Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio 43210, USA.
Angiogenesis, the growth of new blood vessels, plays a vital role in injury curing. Among many known growth factors, the vascular endothelial growth factor (VEGF) is believed to be the most prevailing, efficacious, and long-term signal that is recognized to promote angiogenesis in wounds. Whereas the active role of copper in facilitating angiogenesis has been known for the past 20 years, the specific targets of copper action remained uncertain.
This paper presents initial evidence, showing that inducible VEGF synthesis is related to copper production, and that the angiogenic potential of copper may be harnessed to speed up skin injury contraction and closure.
In physiologically normal proportions, copper sulfate stimulated VEGF expression has be proven to mutate human keratinocytes. Copper used some of the mechanisms utilized by hypoxia to regulate VEGF synthesis. Topical copper sulfate accelerated the closure of excisional murine skin wounds, allowing incisions to cure themselves by secondary intention. Copper-sensitive mechanisms regulate important intermediaries of injury healing, such as angiogenesis and extracellular matrix rejuvenating.
Copper-based therapeutics represents a feasible approach to stimulate skin injury healing, including it among the likely components of natural skincare treatments.
Some types of copper peptide complexes possess both tissue defense and repairing abilities. Copper has protective and rejuvenating actions on several organ systems including skin, bone, hair follicles, gastric mucosa, and intestinal linings. These types of copper complexes are increasingly included in cosmetic skin and hair care products because of their ability to trigger the regeneration of the skin. You will find them among other dermatological skin rejuvenating options, such as chemical peels, laser resurfacing and dermabrasion, to enhance post-treatment skin recovery.
Aging Reversal Of Skin
The principal interest in copper peptides is in the area of reversing the effects of human aging and UV harm of the human skin. During the aging process, skin turns thinner and is prone to accumulating various skin lesions and blemishes. Within the dermis and epidermis, thin and subcutaneous fat cells diminish in quantity.
Several studies have shown that the application of copper peptide creams to the human skin is even more efficient in promoting collagen production than retinoic acid or vitamin C. It also increases the thickness of the epidermis and dermis, improves cellular regeneration, reduces wrinkles and removes skin blemishes such as blotchiness and sun damage marks.
A new sensitive skincare product is the latest answer for all your dermal ailments, including scars and imperfections. Biological ingredients ensure a safe and promising skin rejuvenation process.